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She was an adult actress active in the 1970s Los Angeles pornography scene, appearing in about 300 films and loops. Born in San Diego, California, she was well-known for having a youthful, "girl next door" appeal.
Bond was a member of the AVN Hall of Fame and the X-Rated Critics Organization Hall of Fame.
Bond began her career in softcore exploitation films produced by Harry Novak in the late 1960s before moving on to hardcore films in the early 1970s. She reportedly earned $100 a day for hardcore work and $30 a day for soft-core. During this period, she frequently appeared with her then-boyfriend, porn actor Ric Lutze.
Bond was one of the first porn stars to get a breast enlargement, which was reportedly paid for by Novak. She also appeared under the names Mindy Brandt, Michelle Combe, Annie Hall, Diane Lee, Priscilla Lee, Lilly Lovetree, Sally Martin and Lotta Rocks.
Bond died June 2, 1996 of cirrhosis of the liver. In 1999, Rene Bond was posthumously inducted into the Legends of Erotica Hall of Fame.